CFL2 Antibody (N-term)

APR15434G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15434G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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CFL2 Antibody (N-term)

品牌	Leading Biology	貨號	APR15434G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CFL2 antibody (N-term).
分子量	18737 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus matrix. Cytoplasm, cytoskeleton
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	25-54 aa
靶點	This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2.
亞型	Rabbit Ig
基因ID	1073
UniProt ID	Q9Y281
功能	Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity).
總結(jié)	This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	Cofilin-2, Cofilin, muscle isoform, CFL2
圖像	Western blot analysis of lysate from NCI-H1299 cell line, using CFL2 Antibody (N-term)(Cat. APR15434G). APR15434G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. CFL2 Antibody (N-term) (APR15434G)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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