AES Antibody (C-term)

APR14860G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14860G		100 μl / ￥4950

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AES Antibody (C-term)

品牌	Leading Biology	貨號	APR14860G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AES antibody (C-term).
分子量	21970 Da
細胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	156-184 aa
靶點	This AES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the C-terminal region of human AES.
亞型	Rabbit Ig
通用名	GRG, GRG5
基因ID	166
UniProt ID	Q08117
功能	Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
總結(jié)	The protein encoded by this gene is similar in sequence tothe amino terminus of Drosophila enhancer of split groucho, aprotein involved in neurogenesis during embryonic development. Theencoded protein, which belongs to the groucho/TLE family ofproteins, can function as a homooligomer or as a heteroologimerwith other family members to dominantly repress the expression ofother family member genes. Three transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Amino-terminal enhancer of split, Amino enhancer of split, Gp130-associated protein GAM, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, AES, GRG, GRG5
圖像	Western blot analysis of AES (arrow) using rabbit polyclonal AES Antibody (C-term) (Cat. APR14860G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AES gene. AES Antibody (C-term) (Cat. APR14860G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AES antibody detected the AES protein (arrow).
說明書	Product Datasheet Protocol
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