全部產品分類
品牌 |
Leading Biology | 貨號 |
APR16023G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FREM2 antibody.
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分子量 |
351157 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein; Extracellular side
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse
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靶點 |
FREM2;
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. May be required for epidermal adhesion.
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總結 |
FREM2 Antibody: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IF, ICC, E
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圖像 |
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說明書 |
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數(shù)量 |
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