CRMP1 Antibody

APR11675G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR11675G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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CRMP1 Antibody

品牌	Leading Biology	貨號	APR11675G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRMP1 antibody.
分子量	62184 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes and the mitotic spindle during metaphase
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	CRMP1; This antibody is expected to recognize only the longest isoform of CRMP-1.
亞型	IgG
通用名	DPYSL1, ULIP3
基因ID	1400
UniProt ID	Q14194
功能	Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.
總結(jié)	CRMP1 Antibody: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
圖像	Western blot analysis of CRMP1 in rat brain tissue lysate with CRMP1 antibody at (A) 1 and (B) 2 μg/mL. Immunohistochemistry of CRMP-1 in mouse brain tissue with CRMP-1 antibody at 2.5 μg/mL. Immunofluorescence of CRMP1 in mouse brain tissue with CRMP1 antibody at 5 μg/mL.
說明書	Product Datasheet Protocol
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