品牌 |
Leading Biology | 貨號(hào) |
APR10787G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZIP10 antibody.
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分子量 |
94132 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
Slc39a10; This antibody will not cross-react with the zinc transporter ZIP11.
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亞型 |
IgG
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通用名 |
KIAA1265, ZIP10
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基因ID |
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UniProt ID |
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功能 |
May act as a zinc-influx transporter.
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總結(jié) |
ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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圖像 |
Western blot analysis of ZIP10 in human spleen tissue lysate with ZIP10 antibody at (A) 1 and (B) 2 μg/mL. Immunohistochemistry of ZIP10 in human spleen tissue with ZIP10 antibody at 2.5 μg/mL. |
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說(shuō)明書(shū) |
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數(shù)量 |
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