GABRG3 Antibody (N-term)

APR11977G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR11977G		100 μl / ￥4950

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GABRG3 Antibody (N-term)

品牌	Leading Biology	貨號	APR11977G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABRG3 antibody (N-term).
分子量	54289 Da
細(xì)胞定位	Antigen Cellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	1-29 aa
靶點(diǎn)	This GABRG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human GABRG3.
亞型	Rabbit Ig
基因ID	2567
UniProt ID	Q99928
功能	GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
總結(jié)	GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999 [PubMed 10414349]). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Gamma-aminobutyric acid receptor subunit gamma-3, GABA(A) receptor subunit gamma-3, GABRG3
圖像	Western blot analysis of lysates from K562 cell line and human brain, testis tissue lysate(from left to right), using GABRG3 Antibody (N-term)( APR11977G). APR11977G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. Western blot analysis of GABRG3 Antibody (N-term) (Cat. APR11977G) in mouse brain tissue lysates (35ug/lane). GABRG3 (arrow) was detected using the purified Pab. GABRG3 Antibody (N-term) (Cat. APR11977G) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GABRG3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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