品牌 |
Leading Biology | 貨號 |
APR16953G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality JLP (SPAG9) antibody (N-term).
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分子量 |
146205 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Note=Perinuclear distribution in response to stress signals such as UV radiation
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
91-120 aa
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靶點(diǎn) |
This JLP (SPAG9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the N-terminal region of human JLP (SPAG9).
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亞型 |
Rabbit Ig
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通用名 |
HSS, KIAA0516, MAPK8IP4, SYD1
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基因ID |
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UniProt ID |
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功能 |
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction.
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總結(jié) |
SPAG9, which is abundantly expressed in testicular haploid germ cells, is recognized by sperm-agglutinating antibodies and implicated in infertility.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
C-Jun-amino-terminal kinase-interacting protein 4, JIP-4, JNK-interacting protein 4, Cancer/testis antigen 89, CT89, Human lung cancer oncogene 6 protein, HLC-6, JNK-associated leucine-zipper protein, JLP, Mitogen-activated protein kinase 8-interacting protein 4, Proliferation-inducing protein 6, Protein highly expressed in testis, PHET, Sperm surface protein, Sperm-associated antigen 9, Sperm-specific protein, Sunday driver 1, SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
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圖像 |
Western blot analysis of SPAG9(arrow) using rabbit polyclonal SPAG9 (N-term) Antibody (Cat. APR16953G).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPAG9 (N-term) gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human testis tissue reacted with SPAG9 antibody (N-term) (Cat. APR16953G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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