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GPR77 Antibody (C-term)

APR16604G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR16604G		100 μl / ￥4950

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GPR77 Antibody (C-term)

品牌	Leading Biology	貨號	APR16604G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPR77 antibody (C-term).
分子量	36080 Da
細胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應性	Human
免疫原	297-325 aa
靶點	This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
亞型	Rabbit Ig
通用名	C5L2, GPR77
基因ID	27202
UniProt ID	Q9P296
功能	Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
總結(jié)	The anaphylatoxins C3a (see MIM 120700), C4a (see MIM120810), and C5a are cationic fragments generated during thecomplement cascade that participate in host defense. In the case ofinappropriate complement activation, anaphylatoxins may be involvedin autoimmunity and sepsis. C5L2 is coexpressed with the C5areceptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophilsand may modulate C5AR activity (Gerard et al., 2005 [PubMed16204243]).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, E
稀釋方法	WB~~1:1000
別名	C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
圖像	GPR77 Antibody (C-term) (Cat. APR16604G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GPR77 antibody detected the GPR77 protein (arrow).
說明書	Product Datasheet Protocol
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