GATE16 Antibody (N-term)

AMM04715G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM04715G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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GATE16 Antibody (N-term)

品牌	Leading Biology	貨號	AMM04715G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GATE16 antibody (N-term).
分子量	13667 Da
細胞定位	Antigen Cellular Localization: Golgi apparatus. Cytoplasmic vesicle, autophagosome
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	1-28 aa
靶點	This GATE16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human GATE16.
亞型	Rabbit Ig
通用名	FLC3A, GEF2
基因ID	11345
UniProt ID	P60520
功能	Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
總結(jié)	Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Gamma-aminobutyric acid receptor-associated protein-like 2, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, Golgi-associated ATPase enhancer of 16 kDa, GATE-16, MAP1 light chain 3-related protein, GABARAPL2, FLC3A, GEF2
圖像	GATE16 Antibody (N-term) (Cat. AMM04715G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GATE16 antibody detected the GATE16 protein (arrow). GATE16 Antibody (N-term) (Cat. AMM04715G) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the GATE16 antibody detected the GATE16 protein (arrow).
說明書	Product Datasheet Protocol
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