品牌 |
Leading Biology | 貨號 |
APR14319G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DSG1 antibody (Center).
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分子量 |
113748 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
471-499 aa
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靶點 |
This DSG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the Central region of human DSG1.
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亞型 |
Rabbit Ig
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通用名 |
CDHF4
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基因ID |
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UniProt ID |
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功能 |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
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總結 |
Desmosomes are cell-cell junctions between epithelial,myocardial and certain other cell types. Desmoglein 1 is acalcium-binding transmembrane glycoprotein component of desmosomesin vertebrate epithelial cells. Currently, three desmogleinsubfamily members have been identified and all are members of thecadherin cell adhesion molecule superfamily. These desmoglein genefamily members are located in a cluster on chromosome 18. Theprotein encoded by this gene has been identified as the autoantigenof the autoimmune skin blistering disease pemphigus foliaceus.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen, DSG1, CDHF4
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圖像 |
DSG1 Antibody (Center) (Cat. APR14319G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DSG1 antibody detected the DSG1 protein (arrow). DSG1 Antibody (Center) (APR14319G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DSG1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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