全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR16795G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IBSP antibody (N-term).
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分子量 |
35148 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
70-99 aa
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靶點(diǎn) |
This IBSP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human IBSP.
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亞型 |
Rabbit Ig
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通用名 |
BNSP
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基因ID |
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UniProt ID |
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功能 |
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
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總結(jié) |
The protein encoded by this gene is a major structuralprotein of the bone matrix. It constitutes approximately 12% of thenoncollagenous proteins in human bone and is synthesized byskeletal-associated cell types, including hypertrophicchondrocytes, osteoblasts, osteocytes, and osteoclasts. The onlyextraskeletal site of its synthesis is the trophoblast. Thisprotein binds to calcium and hydroxyapatite via its acidic aminoacid clusters, and mediates cell attachment through an RGD sequencethat recognizes the vitronectin receptor.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, Integrin-binding sialoprotein, IBSP, BNSP
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圖像 |
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說明書 |
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數(shù)量 |
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