BAG2 Antibody (C-term)

APR07076G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07076G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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BAG2 Antibody (C-term)

品牌	Leading Biology	貨號	APR07076G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAG2 antibody (C-term).
分子量	23772 Da
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	148-176 aa
靶點	This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.
亞型	Rabbit Ig
基因ID	9532
UniProt ID	O95816
功能	Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
總結(jié)	BAG proteins compete with Hip for binding to theHsc70/Hsp70 ATPase domain and promote substrate release. All theBAG proteins have an approximately 45-amino acid BAG domain nearthe C terminus but differ markedly in their N-terminal regions. Thepredicted BAG2 protein contains 211 amino acids. The BAG domains ofBAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPasedomain in vitro and in mammalian cells. All 3 proteins bind withhigh affinity to the ATPase domain of Hsc70 and inhibit itschaperone activity in a Hip-repressible manner. [provided byRefSeq].
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
圖像	BAG2 Antibody (C-term) (Cat. APR07076G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow). BAG2 Antibody (C-term) (APR07076G)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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