品牌 |
Leading Biology | 貨號 |
APR11474G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AVPR1B antibody (C-term).
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分子量 |
46971 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
289-317 aa
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靶點 |
This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.
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亞型 |
Rabbit Ig
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通用名 |
AVPR3, VPR3
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基因ID |
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UniProt ID |
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功能 |
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
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總結(jié) |
The protein encoded by this gene acts as receptor forarginine vasopressin. This receptor belongs to the subfamily ofG-protein coupled receptors which includes AVPR1A, V2R and OXTreceptors. Its activity is mediated by G proteins which stimulate aphosphatidylinositol-calcium second messenger system. The receptoris primarily located in the anterior pituitary, where it stimulatesACTH release. It is expressed at high levels in ACTH-secretingpituitary adenomas as well as in bronchial carcinoids responsiblefor the ectopic ACTH syndrome. A spliced antisense transcript ofthis gene has been reported but its function is not known.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
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圖像 |
All lanes : Anti-AVPR1B Antibody (C-term) at 1:1000 dilution Lane 1: HUVEC whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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說明書 |
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數(shù)量 |
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