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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > NOSTRIN Antibody (Center)

NOSTRIN Antibody (Center)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM06754G 100 μl / ¥4950

NOSTRIN Antibody (Center)

品牌

Leading Biology

貨號

AMM06754G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOSTRIN antibody (Center).

分子量

57660 Da

細(xì)胞定位

Antigen Cellular Localization: Isoform 1: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse

免疫原

296-325 aa

靶點(diǎn)

This NOSTRIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human NOSTRIN.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.

總結(jié)

Nitric oxide (NO) is a potent mediator in biologicprocesses such as neurotransmission, inflammatory response, andvascular homeostasis. NOSTRIN binds the enzyme responsible for NOproduction, endothelial NO synthase (ENOS; MIM 163729), andtriggers the translocation of ENOS from the plasma membrane tovesicle-like subcellular structures, thereby attenuatingENOS-dependent NO production.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN

圖像

NOSTRIN Antibody (Center) (Cat. AMM06754G) western blot analysis in mouse heart tissue and HepG2 cell line lysates (35ug/lane).This demonstrates the NOSTRIN antibody detected the NOSTRIN protein (arrow).

說明書

數(shù)量

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