POF1B Antibody (Center)

AMM07259G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07259G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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POF1B Antibody (Center)

品牌	Leading Biology	貨號(hào)	AMM07259G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POF1B antibody (Center).
分子量	68065 Da
細(xì)胞定位	Antigen Cellular Localization: Cell junction, tight junction
宿主	Rabbit
種屬反應(yīng)性	Mouse
免疫原	337-366 aa
靶點(diǎn)	This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.
亞型	Rabbit Ig
基因ID	79983
UniProt ID	Q8WVV4
功能	Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
總結(jié)	Premature ovarian failure (POF) is characterized byprimary or secondary amenorrhea in women less than 40 years old.Two POF susceptibility regions called 'POF1' and 'POF2' have beenidentified by breakpoint mapping of X-autosome translocations. POF1extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1.This gene, POF1B, resides in the POF2 region. This gene isexpressed at trace levels in mouse prenatal ovary and is barelydetectable or absent from adult ovary, in human and in the mouserespectively. This gene's expression is restricted to epitheliawith its highest expression in the epidermis, and oro-pharyngealand gastro-intestinal tracts. The protein encoded by this genebinds non-muscle actin filaments. The role this gene may play inthe etiology of premature ovarian failure remains to be determined.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Protein POF1B, Premature ovarian failure protein 1B, POF1B
圖像	POF1B Antibody (Center) (Cat. AMM07259G) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the POF1B antibody detected the POF1B protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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