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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > NSMAF Antibody (N-term)

NSMAF Antibody (N-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR17612G 100 μl / ¥4950

NSMAF Antibody (N-term)

品牌

Leading Biology

貨號(hào)

APR17612G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NSMAF antibody (N-term).

分子量

104372 Da

宿主

Rabbit

種屬反應(yīng)性

Mouse

免疫原

28-57 aa

靶點(diǎn)

This NSMAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human NSMAF.

亞型

Rabbit Ig

通用名

FAN

基因ID

UniProt ID

功能

Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N- smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE.

總結(jié)

This gene encodes a WD-repeat protein that binds thecytoplasmic sphingomyelinase activation domain of the 55kD tumornecrosis factor receptor. This protein is required for TNF-mediatedactivation of neutral sphingomyelinase and may play a role inregulating TNF-induced cellular responses such as inflammation.Alternative splicing results in multiple transcript variants.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

WB~~1:1000 IHC-P~~1:10~50

別名

Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation, NSMAF, FAN

圖像

NSMAF Antibody (N-term) (Cat. APR17612G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the NSMAF antibody detected the NSMAF protein (arrow).

NSMAF Antibody (N-term) (Cat. APR17612G)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NSMAF Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

說(shuō)明書(shū)

數(shù)量

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