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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
APR13286G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SFRS7 antibody (N-term).
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分子量 |
27367 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
69-98 aa
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靶點(diǎn) |
This SFRS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human SFRS7.
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亞型 |
Rabbit Ig
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通用名 |
SFRS7
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基因ID |
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UniProt ID |
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功能 |
Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
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總結(jié) |
The protein encoded by this gene is a member of theserine/arginine (SR)-rich family of pre-mRNA splicing factors,which constitute part of the spliceosome. Each of these factorscontains an RNA recognition motif (RRM) for binding RNA and an RSdomain for binding other proteins. The RS domain is rich in serineand arginine residues and facilitates interaction between differentSR splicing factors. In addition to being critical for mRNAsplicing, the SR proteins have also been shown to be involved inmRNA export from the nucleus and in translation. Two transcriptvariants encoding different isoforms have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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