品牌 |
Leading Biology | 貨號 |
APR08078G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNJ8 antibody (N-term).
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分子量 |
47968 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
4-33 aa
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靶點 |
This KCNJ8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of human KCNJ8.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
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總結(jié) |
Potassium channels are present in most mammalian cells,where they participate in a wide range of physiologic responses.The protein encoded by this gene is an integral membrane proteinand inward-rectifier type potassium channel. The encoded protein,which has a greater tendency to allow potassium to flow into a cellrather than out of a cell, is controlled by G-proteins. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
ATP-sensitive inward rectifier potassium channel 8, Inward rectifier K(+) channel Kir61, Potassium channel, inwardly rectifying subfamily J member 8, uKATP-1, KCNJ8
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圖像 |
KCNJ8 Antibody (N-term) (Cat. APR08078G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNJ8 antibody detected the KCNJ8 protein (arrow). KCNJ8 Antibody (N-term) (Cat. APR08078G)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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