品牌 |
Leading Biology | 貨號(hào) |
APR15259G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CALU antibody (C-term).
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分子量 |
37107 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
217-246 aa
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靶點(diǎn) |
This CALU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human CALU.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
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總結(jié) |
The product of this gene is a calcium-binding proteinlocalized in the endoplasmic reticulum (ER) and it is involved insuch ER functions as protein folding and sorting. This proteinbelongs to a family of multiple EF-hand proteins (CERC) thatinclude reticulocalbin, ERC-55, and Cab45 and the product of thisgene. Alternatively spliced transcript variants encoding differentisoforms have been identified.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Calumenin, Crocalbin, IEF SSP 9302, CALU
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圖像 |
CALU Antibody (C-term) (Cat. APR15259G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CALU antibody detected the CALU protein (arrow). CALU Antibody (C-term) (Cat. APR15259G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALU Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書(shū) |
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數(shù)量 |
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