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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > NUMB Antibody (N-term)

NUMB Antibody (N-term)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM06871G 100 μl / ¥4950

NUMB Antibody (N-term)

品牌

Leading Biology

貨號

AMM06871G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NUMB antibody (N-term).

分子量

70804 Da

細(xì)胞定位

Antigen Cellular Localization: Membrane; Peripheral membrane protein.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

1-30 aa

靶點(diǎn)

This NUMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NUMB.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

總結(jié)

The protein encoded by this gene plays a role in thedetermination of cell fates during development. The encodedprotein, whose degradation is induced in a proteasome-dependentmanner by MDM2, is a membrane-bound protein that has been shown toassociate with EPS15, LNX1, and NOTCH1. Four transcript variantsencoding different isoforms have been found for this gene.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

WB~~1:1000 IHC-P~~1:50~100

別名

Protein numb homolog, h-Numb, Protein S171, NUMB

圖像

NUMB Antibody (N-term) (Cat. AMM06871G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NUMB antibody detected the NUMB protein (arrow).

NUMB Antibody (N-term) (Cat. AMM06871G)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NUMB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

說明書

數(shù)量

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