品牌 |
Leading Biology | 貨號(hào) |
AMM05348G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UGT2B15 antibody (Center).
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分子量 |
61036 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
156-185 aa
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靶點(diǎn) |
This UGT2B15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human UGT2B15.
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亞型 |
Rabbit Ig
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通用名 |
UGT2B8
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基因ID |
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UniProt ID |
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功能 |
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
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總結(jié) |
The UGTs are of major importance in the conjugation andsubsequent elimination of potentially toxic xenobiotics andendogenous compounds. UGT2B8 demonstrates reactivity with estriol.See UGT2B4 (MIM 600067).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
FC~~1:10~50
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別名 |
UDP-glucuronosyltransferase 2B15, UDPGT 2B15, HLUG4, UDP-glucuronosyltransferase 2B8, UDPGT 2B8, UDPGTh-3, UGT2B15, UGT2B8
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圖像 |
UGT2B15 Antibody (Center) (Cat. AMM05348G) western blot analysis in NCI-H460(lane 1),HepG2(lane 2),ZR-75-1(lane 3) cell line lysates (35ug/lane).This demonstrates the UGT2B15 antibody detected the UGT2B15 protein (arrow). UGT2B15 Antibody (Center) (Cat. AMM05348G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT2B15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Confocal immunofluorescent analysis of UGT2B15 Antibody (Center) ( AMM05348G) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
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說明書 |
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數(shù)量 |
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