品牌 |
Leading Biology | 貨號(hào) |
APR05477G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UBXN6 Antibody (C-term).
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分子量 |
49754 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the centrosome both in interphase and during mitosis
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
281-309 aa
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靶點(diǎn) |
This UBXN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human UBXN6.
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亞型 |
Rabbit Ig
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通用名 |
UBXD1, UBXDC2
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基因ID |
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UniProt ID |
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功能 |
Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.
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總結(jié) |
UBXN6 acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. UBXN6 is MDM2 stabilization leads to MDM2-dependent TP53 degradation.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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圖像 |
Western blot analysis of UBXN6 Antibody (C-term) (Cat. APR05477G) in mouse kidney tissue lysates (35ug/lane).UBXN6 (arrow) was detected using the purified Pab. UBXN6 Antibody (C-term) (Cat. APR05477G) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UBXN6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書 |
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數(shù)量 |
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