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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
APR12691G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2X5 Receptor antibody.
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分子量 |
51479 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Rat
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靶點(diǎn) |
Peptide (C)RENAIVNVKQSQILHPVKT, corresponding to amino acid residues 437-455 of??rat P2X5 Receptor (Accession?? P51578). Intracellular, C-terminus.
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基因ID |
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UniProt ID |
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總結(jié) |
The P2X5 receptor (P2X5R) belongs to the ligand-gated ion channel P2X family,which is activated by extracellular ATP. To date, seven receptor subtypes named P2X1-P2X7 have been described.1,2,3 All P2X subunits, with the exception of P2X6, can assemble to form homomeric or heteromeric functional channels.4-5 The P2X5R forms a heteromeric receptor with P2X1 receptor. The heteromeric receptor has distinct properties from the P2X1 or P2X5 homomeric receptors.4,6 The different P2X receptors show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly antigen presenting cells, and in microglia. The P2X5 subunit was first cloned from rat heart, and was reported to be expressed in heart, brain, spinal cord and adrenal gland.Recent papers suggested possible roles for P2X5 receptor in differentiation and apoptosis in keratinocytesand ageing rat prostate, respectively.7-10We are pleased to offer a new antibody to our growing line of ligand-gated ion channel P2X antibodies,Anti-P2X5 Receptorantibody.
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形式 |
Affinity purified antibody, Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:200-1:2000
IHC~~1:100
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別名 |
P2X purinoceptor 5, P2X5, ATP receptor, Purinergic receptor, P2rx5
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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