全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17721G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2Y4 Receptor antibody.
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分子量 |
40894 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
Peptide (C)HEES ISRWA DTHQD, corresponding to residues 337-350 of rat P2Y4 (Accession O35811). Intracellular, C-terminus.
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基因ID |
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UniProt ID |
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總結(jié) |
The P2Y receptors belong to the G-protein coupled receptors superfamily. P2Y receptors mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP) and regulate several physiologic responses, among them, cardiac function,platelet aggregation and SMC proliferation.1The mammalian P2Y family currently includes eight functional receptors; P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.2-4The P2Y4-receptor is highly expressed in the placenta and with lower levels at lung and vascular smooth muscle.5The human P2Y4 receptor is highly selective to UTP while rat P2Y4 receptor is equally activated by both UTP and ATP and also by other triphosphate nucleotides such as Ap4A.5Recently it has been shown that P2Y4 receptor is involved in differentiation and cell death of human neuroblastoma SH-SY5Y cells.6Abgent is pleased to offer a highly specific antibody directed against the C terminus domain of the rat P2Y4 receptor.Anti-P2Y4 Receptorantibody (#AG1072) can be used in western blot analysis, immunoprecipitation, indirect flow cytometry, immunocytochemistryand immunohistochemistry, and recognizes P2Y4 in rat samples.
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形式 |
Affinity purified antibody, Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IP
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稀釋方法 |
WB~~1:200-1:2000
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別名 |
P2Y purinoceptor 4, P2Y4, P2ry4, P2y4
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圖像 |
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說明書 |
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數(shù)量 |
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