TNFAIP1 Antibody

AMM08251G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM08251G		0.1 mg / ￥6950

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TNFAIP1 Antibody

品牌	Leading Biology	貨號(hào)	AMM08251G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNFAIP1 antibody.
分子量	Predicted: 35 kDa Observed: 35 kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	TNFAIP1; TNFAIP1 antibody is human, mouse and rat reactive. TNFAIP1 antibody is predicted to not cross-react with other TNFAIP proteins.
亞型	IgG
通用名	BACURD2, EDP1
基因ID	7126
UniProt ID	Q13829
功能	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
總結(jié)	TNFAIP1 is a BTB/POZ domain-containing protein that belongs to the KCTD10/BACURD family which mediates POZ-POZ interactions and chromatin modeling (1,2). The expression of TNFAIP1 is developmentally regulated in a tissue-specific manner and can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells (3). TNFAIP1 may be involved in DNA repair, DNA synthesis, and cell apoptosis. TNFAIP1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus (4,5).
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
圖像	Western blot analysis of TNFAIP1 in mouse brain tissue lysate with TNFAIP1 antibody at 1 μg/ml. Immunohistochemistry of TNFAIP1 in mouse brain tissue with TNFAIP1 antibody at 10 μg/ml.
說(shuō)明書	Product Datasheet Protocol
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