SLC38A4 Antibody

AMM07866G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07866G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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SLC38A4 Antibody

品牌	Leading Biology	貨號(hào)	AMM07866G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC38A4 antibody.
分子量	Predicted: 60 kDa; Observed: 60 kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	SLC38A4; SLC38A4 antibody is human and mouse reactive. SLC38A4 will not cross-react with other members of the SLC38 protein family.
亞型	IgG
通用名	ATA3, NAT3, SNAT4
基因ID	55089
UniProt ID	Q969I6
功能	Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium- independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5.
總結(jié)	SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids (1,2). The transport of cationic amino acids by SLC38A4 is sodium and pH independent, while the transport of neutral amino acids is sodium and pH dependent (2). Recent evidence suggests that SLC38A4 functions as a regulator of protein synthesis downstream of the hepatocyte nuclear factor 4a during liver development (3). It has also been suggested that SLC38A4 has ATPase activity and is critically involved in the maintenance of mitochondrial homeostasis and cell survival (4).
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
圖像	Western blot analysis of SLC38A4 in mouse kidney tissue lysate with SLC38A4 antibody at (A) 1 and (B) 2 μg/ml. Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.
說明書	Product Datasheet Protocol
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