品牌 |
Leading Biology | 貨號(hào) |
AMM06207G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIRREL3 antibody.
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分子量 |
Predicted: 64, 84 kDa Observed: 60 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
KIRREL3; KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
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亞型 |
IgG
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通用名 |
KIAA1867, NEPH2
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基因ID |
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UniProt ID |
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功能 |
Could be involved in the hematopoietic supportive capacity of stroma cells.
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總結(jié) |
KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of KIRREL3 in mouse kidney tissue lysate with KIRREL3 antibody at (A) 1 and (B) 2 μg/ml. Immunohistochemistry of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 5 μg/ml. Immunofluorescence of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 20 μg/ml. |
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說(shuō)明書 |
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數(shù)量 |
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