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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CCL2 Antibody

CCL2 Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APG02471G 0.1 mg / ¥6950

CCL2 Antibody

品牌

Leading Biology

貨號

APG02471G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCL2 antibody.

分子量

Predicted: 11 kDa

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse, Rat

靶點

CCL2;

亞型

IgG

通用名

MCP1, SCYA2

基因ID

UniProt ID

功能

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

總結(jié)

CCL2 Antibody: CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

圖像

Western blot analysis of CCL2 in rat spleen tissue lysate with CCL2 antibody at 1 μg/mL.

Immunohistochemistry of CCL2 in spleen tissue with CCL2 antibody at 5 μg/ml.

Immunofluorescence of CCL2 in human spleen tissue with CCL2 antibody at 20 μg/ml.

說明書

數(shù)量

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