品牌 |
Leading Biology | 貨號 |
AMM06535G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYT1L antibody.
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分子量 |
130 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
MYT1L; At least three isoforms are known to exist. This antibody will only recognize the two longest isoforms.
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亞型 |
IgG
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通用名 |
KIAA1106
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基因ID |
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UniProt ID |
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功能 |
May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendrogalia in the CNS (By similarity).
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總結(jié) |
MYT1L Antibody: The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, E
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圖像 |
Western blot analysis of MYT1L in mouse brain tissue lysate with MYT1L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunofluorescence of MYT1L in human brain with MYT1L antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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