ACSL1 Antibody

APG01518G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01518G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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ACSL1 Antibody

品牌	Leading Biology	貨號(hào)	APG01518G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACSL1 antibody.
分子量	77 kDa
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	ACSL1; At least three isoforms of ACSL1 are known to exist; this antibody will detect all three isoforms.
亞型	IgG
通用名	FACL1, FACL2, LACS, LACS1, LACS2
基因ID	2180
UniProt ID	P33121
功能	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
總結(jié)	ACSL1 Antibody: Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ASCL1 is the major acyl-CoA enzyme in the heart, providing 60-90% of heart ATP. Loss of ASCL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, E
圖像	Western blot analysis of ACSL1 in human lung tissue lysate with ACSL1 antibody at (A) 1 and (B) 2 μg/mL. Immunofluorescence of ASCL1 in human lung tissue with ASCL1 antibody at 20 μg/mL.
說(shuō)明書	Product Datasheet Protocol
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