品牌 |
Leading Biology | 貨號(hào) |
APR17889G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZMYM2 antibody.
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分子量 |
154911 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
ZMYM2; At least two isoforms of ZMYM1 are known to exist; this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members.
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亞型 |
IgG
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通用名 |
FIM, RAMP, ZNF198
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基因ID |
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UniProt ID |
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功能 |
May function as a transcription factor.
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總結(jié) |
ZMYM2 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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圖像 |
Western blot analysis of ZMYM2 in EL4 cell lysate with ZMYM2 antibody at (A) 0.125 and (B) 0.25 μg/mL. Immunocytochemistry of ZMYM2 in HeLa cells with ZMYM2 antibody at 10 μg/mL. Immunofluorescence of ZMYM2 in HeLa cells with ZMYM2 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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