品牌 |
Leading Biology | 貨號 |
AMM08177G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TFF3 antibody.
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分子量 |
Predicted: 10 kDa Observed: 11 kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix. Cytoplasm
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
TFF3; TFF3 antibody is predicted to not cross-react with other TFF family members.
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亞型 |
IgG
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通用名 |
ITF, TFI
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基因ID |
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UniProt ID |
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功能 |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
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總結(jié) |
TFF3 Antibody: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of TFF3 in human colon tissue lysate with TFF3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of TFF3 in human small intestine tissue with TFF3 antibody at 2.5 μg/mL. Immunofluorescence of TFF3 in Human Small Intestine tissue with TFF3 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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