HVCN1 Antibody

APR16793G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR16793G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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HVCN1 Antibody

品牌	Leading Biology	貨號(hào)	APR16793G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HVCN1 antibody.
分子量	31683 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	HVCN1;
亞型	IgG
通用名	VSOP
基因ID	84329
UniProt ID	Q96D96
功能	Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.
總結(jié)	HVCN1 Antibody: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
圖像	Western blot analysis of HVCN1 in human spleen tissue lysate with HVCN1 antibody at (A) 0.5 and (B) 1 μg/mL. Immunohistochemistry of HVCN1 in rat spleen tissue with HVCN1 antibody at 5 μg/mL. Immunofluorescence of HVCN1 in Rat Spleen cells with HVCN1 antibody at 20 μg/mL.
說(shuō)明書(shū)	Product Datasheet Protocol
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