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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM05661G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CaBP8 antibody.
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分子量 |
24837 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
CALN1;
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亞型 |
IgG
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通用名 |
CABP8
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基因ID |
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UniProt ID |
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功能 |
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.
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總結(jié) |
CaBP8 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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