品牌 |
Leading Biology | 貨號(hào) |
APR13626G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SYNGR1 antibody.
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分子量 |
25456 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
SYNGR1;
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Involved in the regulation of short-term and long-term synaptic plasticity.
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總結(jié) |
SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 μg/mL. Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 μg/mL. |
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說(shuō)明書(shū) |
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數(shù)量 |
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