TTC5 Antibody

AMM08364G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM08364G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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TTC5 Antibody

品牌	Leading Biology	貨號(hào)	AMM08364G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TTC5 antibody.
分子量	48928 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	TTC5;
亞型	IgG
基因ID	91875
UniProt ID	Q8N0Z6
功能	Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
總結(jié)	TTC5 Antibody: Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
別名	TTC5 Antibody: Strap, Tetratricopeptide repeat protein 5, Stress-responsive activator of p300, TPR repeat protein 5, tetratricopeptide repeat domain 5
圖像	Western blot analysis of TTC5 in RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL. Immunohistochemistry of TTC5 in mouse brain tissue with TTC5 antibody at 10 μg/mL. Immunofluorescence of TTC5 in Mouse Brain cells with TTC5 antibody at 20 μg/mL.
說(shuō)明書(shū)	Product Datasheet Protocol
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