CIKS Antibody

APR15447G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR15447G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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CIKS Antibody

品牌	Leading Biology	貨號(hào)	APR15447G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CIKS antibody.
分子量	63 kDa
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	TRAF3IP2;
亞型	IgG
通用名	C6orf2, C6orf4, C6orf5, C6orf6
基因ID	10758
UniProt ID	O43734
功能	Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
總結(jié)	CIKS Antibody: Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB associates with IκB proteins in the cell cytoplasm, which inhibit NF-κB activity. IκB is phosphorylated by IκB kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-κB activator 1). CIKS directly interacts with IKKγ. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
別名	CIKS Antibody: ACT1, CIKS, C6orf2, C6orf4, C6orf5, C6orf6, CANDF8, PSORS13, Adapter protein CIKS, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3 interacting protein 2
圖像	Western blot analysis of CIKS expression in human placenta tissue lysate with CIKS antibody at 1 μg /ml. Immunohistochemistry of CIKS in human lung tissue with CIKS antibody at 5 μg/mL. Immunofluorescence of CIKS in Human Lung cells with CIKS antibody at 20 μg/mL.
說明書	Product Datasheet Protocol
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