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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser129 Alpha Synuclein Antibody品牌 |
Leading Biology | 貨號 |
APR12815G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser129 Alpha Synuclein antibody.
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分子量 |
15 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Rat
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靶點(diǎn) |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser129 conjugated to KLH.
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基因ID |
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UniProt ID |
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總結(jié) |
Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Mutation of the alpha-synuclein gene is associated with familial forms of PD (Newmann et al., 2002). Recent evidence suggests that phosphorylation of alpha-synuclein at ser129 plays a role in the formation of inclusions in PD (Smith et al., 2005; Masliah et al., 2005).
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形式 |
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:1000
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別名 |
Alpha-synuclein, Snca
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圖像 |
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說明書 |
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數(shù)量 |
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