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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser58 14-3-3 Protein Antibody品牌 |
Leading Biology | 貨號(hào) |
APR12822G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser58 14-3-3 Protein antibody.
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分子量 |
29 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Rat
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靶點(diǎn) |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58 conjugated to KLH.
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基因ID |
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UniProt ID |
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總結(jié) |
14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004; Dougherty and Morrison, 2004). The14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking. These functions of 14-3-3 proteins are facilitated by, if not dependent on, its dimeric structure. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation (Woodcock et al., 2003).
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形式 |
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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稀釋方法 |
WB~~ 1:1000
IF~~ 1:500
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別名 |
14-3-3 protein beta/alpha, Prepronerve growth factor RNH-1, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed, Ywhab
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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