RAB1A Antibody (C-Terminus)

AMM07451G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07451G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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RAB1A Antibody (C-Terminus)

品牌	Leading Biology	貨號	AMM07451G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAB1A antibody (C-Terminus).
分子量	22678 Da
細(xì)胞定位	Antigen Cellular Localization: Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome. Note=Alternates between membrane-associated and cytosolic forms
宿主	Goat
種屬反應(yīng)性	Human, Mouse, Rat, Monkey
靶點(diǎn)	Detects total Rab1 protein by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab1a and GFP-Rab1b cds.
亞型	IgG
通用名	RAB1
基因ID	5861
UniProt ID	P62820
功能	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.
總結(jié)	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF
稀釋方法	IF (1:100 - 1:250), IHC-P (5 μg/ml), WB (1:250 - 1:2000),
別名	RAB1A, GTP binding protein Rab1a, YPT1-related protein, Rab GTPase YPT1 homolog, RAB1, Ras-related protein Rab-1A, YPT1
圖像	Anti-RAB1A / RAB1 antibody IHC staining of human small intestine. Anti-RAB1A / RAB1 antibody IHC staining of human kidney. Immunofluorescence - anti-Rab1 antibody in COS-7 cells at 1:50 dilution.
說明書	Product Datasheet Protocol
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