全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM08773G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRG4 / TLE4 antibody (N-Terminus).
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分子量 |
83755 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
The peptide sequence of this antibody is corresponding to amino acids of human 1-50aa. This antibody is predicted to recognize mouse and rat TLE4 protein because of synthesized peptide amino acid 100% homology with mouse and rattus TLE4 protein.
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亞型 |
IgG
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通用名 |
GRG4, KIAA1261
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基因ID |
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UniProt ID |
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功能 |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
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總結(jié) |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:1000 - 1:10000), IHC-P (10 μg/ml), WB (1:500 - 1:1000),
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別名 |
TLE4, BCE1, BCE-1, E(spI), Enhancer of split groucho 4, ESG, ESG4, GRG4, Protein BCE-1, KIAA1261, R-esp2, B lymphocyte gene 1
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圖像 |
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說明書 |
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數(shù)量 |
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