Angiogenin / ANG Antibody (Internal)

APG01870G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01870G		50 μg / ￥4950

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Angiogenin / ANG Antibody (Internal)

品牌	Leading Biology	貨號(hào)	APG01870G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Angiogenin / ANG antibody (Internal).
分子量	17kDa
細(xì)胞定位	Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	Human ANG. Two alternatively spliced transcript variants have been observed.
通用名	RNASE5
基因ID	283
UniProt ID	P03950
功能	Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
總結(jié)	Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF
稀釋方法	IHC-P (5 μg/ml), WB (1-2 μg/ml),
別名	Angiogenin, 3.1.27.-, Ribonuclease 5, RNase 5, ANG, RNASE5
圖像	Anti-Angiogenin / ANG antibody IHC staining of human kidney. Immunofluorescence of ANG in human liver tissue with ANG antibody at 20 ug/ml. Western blot analysis of ANG in rat liver tissue lysate with Ang antibody at (A) 1 and (B) 2 ug/ml.
說(shuō)明書	Product Datasheet Protocol
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