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C11orf2 / Fat-Free Antibody (C-Terminus)品牌 |
Leading Biology | 貨號 |
APR15187G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality C11orf2 / Fat-Free antibody (C-Terminus).
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分子量 |
86kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
Human C11orf2 / Fat-Free. At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms.
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通用名 |
ANG2, C11orf2, C11orf3, FFR
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基因ID |
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UniProt ID |
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功能 |
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi networkl (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN.
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總結(jié) |
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi networkl (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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別名 |
Vacuolar protein sorting-associated protein 51 homolog, Another new gene 2 protein, Protein fat-free homolog, VPS51, ANG2, C11orf2, C11orf3, FFR
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圖像 |
Anti-C11orf2 / Fat-Free antibody IHC staining of human placenta. Western blot analysis of Fat Free in mouse brain tissue lysate with Fat Free antibody at 1 ug/ml. |
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說明書 |
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數(shù)量 |
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