全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR07615G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOK1 antibody (C-Terminus).
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分子量 |
52kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Cytoplasm. Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
peptide corresponding to amino acids near the carboxy terminus of human p62dok
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基因ID |
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UniProt ID |
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功能 |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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總結(jié) |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, ICC
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稀釋方法 |
IHC-P (5 μg/ml), WB (0.5-1 μg/ml),
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別名 |
Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62, DOK1
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圖像 |
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說明書 |
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數(shù)量 |
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