ESRRA / ERR Alpha Antibody (Ligand-binding Domain)

AMM04453G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM04453G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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ESRRA / ERR Alpha Antibody (Ligand-binding Domain)

品牌	Leading Biology	貨號(hào)	AMM04453G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ESRRA / ERR Alpha antibody (Ligand-binding Domain).
分子量	46kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00407, ECO:0000269\|PubMed:18063693}
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Hamster, Monkey, Pig, Horse, Bovine, Dog
靶點(diǎn)	Human ESRRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ESRRG (60%).
通用名	ERR1, ESRL1, NR3B1
基因ID	2101
UniProt ID	P11474
功能	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
總結(jié)	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P
稀釋方法	IHC-P (11-21 μg/ml)
別名	Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1, ESRRA, ERR1, ESRL1, NR3B1
圖像	Anti-ESRRA / ERR Alpha antibody IHC of human Ovary, Carcinoma. Anti-ESRRA / ERR Alpha antibody IHC of human Lung, Non-Small Cell Carcinoma. Anti-ESRRA antibody AMM04453G IHC of human breast carcinoma.
說明書	Product Datasheet Protocol
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ESRRA / ERR Alpha Antibody (Ligand-binding Domain)