USO1 Antibody (C-term)

AMM08444G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM08444G		100 μl / ￥4950

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USO1 Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMM08444G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USO1 antibody (C-term).
分子量	H=108,109 KDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	932-960 aa
靶點(diǎn)	This USO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 932-960 amino acids from the C-terminal region of human USO1.
通用名	VDP
基因ID	8615
UniProt ID	O60763
功能	General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
總結(jié)	The protein encoded by this gene is a peripheral membraneprotein which recycles between the cytosol and the Golgi apparatusduring interphase. It is regulated by phosphorylation:dephosphorylated protein associates with the Golgi membrane anddissociates from the membrane upon phosphorylation. Ras-associatedprotein 1 recruits this protein to coat protein complex II (COPII)vesicles during budding from the endoplasmic reticulum, where itinteracts with a set of COPII vesicle-associated SNAREs to form acis-SNARE complex that promotes targeting to the Golgi apparatus.Transport from the ER to the cis/medial Golgi compartments requiresthe action of this gene product, GM130 and giantin in a sequentialmanner.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P
稀釋方法	IHC-P~~1:10~50 WB~~1:1000
別名	General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
圖像	USO1 Antibody (C-term) (AMM08444G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of USO1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. All lanes : Anti-USO1 Antibody (C-term) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 108 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
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