全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17788G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HUMAN-SHB(Y268) antibody.
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分子量 |
H=55,31;M=55 KDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
250-290 aa
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靶點(diǎn) |
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from human.
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基因ID |
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UniProt ID |
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功能 |
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
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總結(jié) |
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
FC, WB
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稀釋方法 |
WB~~1:1000
FC~~1:25
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別名 |
SH2 domain-containing adapter protein B, SHB
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圖像 |
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說明書 |
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數(shù)量 |
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