品牌 |
Leading Biology | 貨號(hào) |
AMM05113G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-SDHB antibody.
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分子量 |
31630 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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通用名 |
SDH, SDH1
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基因ID |
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UniProt ID |
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功能 |
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
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總結(jié) |
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E, EIA
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別名 |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, 1.3.5.1, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1
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圖像 |
AMM05113G (0.03 μg/ml) staining of Human Liver lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
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說(shuō)明書 |
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數(shù)量 |
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