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Polyclonal Antibodies >
Goat Anti-Renalase (aa 224 to 233) Antibody品牌 |
Leading Biology | 貨號 |
APG03367G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-Renalase (aa 224 to 233) antibody.
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分子量 |
37847 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse
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亞型 |
IgG
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通用名 |
C10orf59
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the oxidation of the less abundant alpha- NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
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總結(jié) |
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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別名 |
Renalase, 1.6.3.5, Monoamine oxidase-C, MAO-C, alpha-NAD(P)H oxidase/anomerase, RNLS, C10orf59
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圖像 |
APG03367G (0.1 μg/ml) staining of Mouse Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. APG03367G (2 μg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. |
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說明書 |
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數(shù)量 |
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