Goat Anti-CBR1 Antibody

AMM04926G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM04926G		0.1 mg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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Goat Anti-CBR1 Antibody

品牌	Leading Biology	貨號(hào)	AMM04926G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-CBR1 antibody.
分子量	30375 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	CBR, CRN
基因ID	873
UniProt ID	P16152
功能	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
總結(jié)	Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.
形式	0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
別名	Carbonyl reductase [NADPH] 1, 1.1.1.184, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], 1.1.1.197, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase, 1.1.1.189, CBR1, CBR, CRN
圖像	AMM04926G staining (0.2 μg/ml) of Human Liver lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. AMM04926G (3 μg/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.
說明書	Product Datasheet Protocol
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